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SauCas9 Genome Editor - [In Vivo] [Small Animal Testing Center (SATC)] [Mouse] Matched Fields: category : Genome Editor guide : Ai9 SaCas9 Guide A Ai9 SaCas9 Guide B Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
SaCas9 Genome Editor - [In Vivo] [Delivery Systems Initiative] [Mouse] Matched Fields: category : Genome Editor guide : Sa_Ai9_L Sa_Ai9_R Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
sNLS-SpCas9-sNLS Genome Editor - [In Vivo, In Vitro] [Small Animal Testing Center (SATC), Collaborative Opportunity Fund, Delivery Systems Initiative] [Human, Mouse] Matched Fields: category : Genome Editor guide : Ai14 gRNA SpCas9 with N- and C-terminal SV40 NLS Show Experiments (5) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system

Type	Subtype	Name	Description	Source	View Associated..
Cas Nuclease	Cas9	SauCas9			Show Experiments (1) Independent validation for Asokan Delivery Team: Evolving High Potency AAV Vectors for Neuromuscular Genome Editing.
Cas Nuclease	Cas9	SaCas9		Leong Lab	Show Experiments (1) FUS (focused ultrasound) array validation in Ai9 mice
Cas Nuclease	Cas9	sNLS-SpCas9-sNLS	SpCas9 with N- and C-terminal SV40 NLS	Aldevron 9212-5MG	Show Experiments (5) Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Independent validation of Gong delivery platform using RNP-loaded nanocages to deliver CRISPR/Cas9 to mouse brain Testing different ratios of Lipofectamine-RNPs after 24 hours for determination of positive control Imaging quantification of transfection efficiency with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on the liver-on-chip model system Quantification of transfection efficiency by flow cytometry with varying dosages of nanoparticles encapsulated with Cas9/sgRNA RNP on liver-on-chip model system

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